PROTOCOL
INTELLIGENCE
Reports. Comparisons. Answers.
Long-term administration of NMN mitigated age-associated physiological decline in mice, with no obvious toxicity over 12 months.
DR. SHIN-ICHIRO IMAI
WASHINGTON UNIVERSITY SCHOOL OF MEDICINE
Mills et al., Cell Metabolism (2016) ↗
NAD+ levels fall with age, and restoring them supports the sirtuin enzymes that defend cells - making NAD+ boosters a leading focus of aging research.
DR. DAVID SINCLAIR
HARVARD MEDICAL SCHOOL
Rajman, Chwalek & Sinclair, Cell Metabolism (2018) ↗
In a randomized, placebo-controlled human trial, NMN improved skeletal-muscle insulin sensitivity in prediabetic women.
DR. JUN YOSHINO & DR. SAMUEL KLEIN
WASHINGTON UNIVERSITY
Yoshino et al., Science (2021) ↗
NMN and NR have emerged as the most promising NAD+ precursors, now moving from animal studies into human clinical trials.
DR. JOSEPH A. BAUR
UNIVERSITY OF PENNSYLVANIA
Yoshino, Baur & Imai, Cell Metabolism (2018) ↗
Independent, peer-reviewed research on NAD+ biology. These scientists are not affiliated with, and do not endorse, Celyfe. Statements describe published NAD+ science in general, not Celyfe products or outcomes.
HOW CELYFE
COMPARES
Precision delivery vs. conventional supplementation.
| FEATURE | CELYFE | TRU NIAGEN | ELYSIUM BASIS | GENERIC NMN |
|---|---|---|---|---|
| FORM | Subcutaneous Pen | Oral Capsule | Oral Capsule | Oral Powder/Capsule |
| PRECURSOR | NAD+ (direct) | NR (Niagen®) | NR + Pterostilbene | NMN (varies) |
| DOSAGE | 50mg/day | 300mg/day | 250mg NR/day | 250-500mg/day |
| BIOAVAILABILITY | High (subcutaneous) | Standard (oral) | Standard (oral) | Standard (oral) |
| TESTED | Yes | Yes | Yes | Varies |
| PROTOCOL SUPPORT | Full 5-pillar system | Standalone | Standalone | None |
| PRICE / MONTH | €149 | €47 | €60 | €20-40 |
*Comparison based on publicly available product information as of February 2026. Bioavailability figures are estimates based on published research on delivery methods. Individual results may vary.
STILL
WONDERING?
Hear it from the scientists and
biohackers leading the NAD+ revolution.
The Biology of Slowing & Reversing Aging
Dr. David Sinclair × Huberman Lab
NAD & NAD Precursors - Help or Hype?
Dr. Peter Attia × Dr. Matt Kaeberlein
NAD+ & Resveratrol Levels Affect Aging
Dr. David Sinclair × Dr. Rhonda Patrick
The Potential Power of NAD+
Dr. David Sinclair × Longevity Research
NMN, NR, Resveratrol & Longevity Molecules
Dr. David Sinclair × Dr. Peter Attia
Longevity Roundtable - The Science of Aging
Dr. Peter Attia × Austad, Miller & Kaeberlein
QUESTIONS
& ANSWERS
Everything you need to know about the CELYFE system.